Fungal metabolites: structural diversity as incentive for anticancer drug development

Autor:	Harald Gross, Hendrik Greve, Gabriele M. König, Alexander Pontius, Ietidal E. Mohamed, Stefan Kehraus
Rok vydání:	2010
Předmět:	Drug development medicine Cancer therapy Cancer Structural diversity Plant Science Pharmacology Biology medicine.disease Anticancer drug Marine fungi Biotechnology
Zdroj:	Phytochemistry Reviews. 9:537-545
ISSN:	1572-980X 1568-7767
DOI:	10.1007/s11101-010-9198-5
Popis:	Natural products play an important role in the development of anticancer drugs. To date, predominantly metabolites from plants and bacteria served as lead structures for anticancer agents. Fungal metabolites and derivatives thereof are much less investigated for their potential in cancer therapy. There are, however, some promising candidates derived from fungi in clinical phases I and II studies. This review gives an overview on the role of natural products in cancer therapy and summarises some of the latest results of our group in this area.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::40753c1d72a913eb21cfa09c2033c818 https://doi.org/10.1007/s11101-010-9198-5 Zobrazit plný text záznamu Full text from SpringerLink