| Popis: |
The drug dependants are at risk of malnutrition particularly of different vitamins including A, C and E. vitamins. The malnutrition in these patients may be a consequence of alterations in the contribution, the absorption or in the metabolism of these nutrients, or for an increase their request. The present study was conducted on 150 drug dependants aged 12-58 years with the essential inclusion criteria i.e positive history and laboratory detection of reported substance abuse and major exclusion criteria as chronic disease (hepatic, renal, and gastrointestinal). From every drug dependant a history was taken and detection of substance abuse by enzyme immunoassay method ( EMIT) and thin layer chromatography was done. Also measurement of antioxidants status of s carotene, a tocopherol and vitamin C by using calorimetric method while plasma level of the metabolic end products of nitric oxide (nitrite and nitrate) using Greiss reaction. The results of the present study showed that, the mean age of the studied drug dependants was 24.19+7.84 with ranged between 12 and 57 years. They addicted to consumption of drug of abuse, specifically cannabis, morphine, barbiturates and benzodiazepines. In this study, the proportion of the low social participants was high (66.6%) and the proportion of the high educational level participants was "3.3%". Moreover, the majority of the individuals were below 30 years, which reflect that consumption of drugs abuse affected fundamentally the young adult sector. In our locality, substances abuse mainly in males and revealed marked affection of them. The majority of the drug dependants were abuser of opiates "tramadol", benzodiazepines "Apetryl", Cannabis "bango" and barbiturates "comidal". Multiplicity of abusing substances by the same person was common. The affection of number of abused substances is marked in the plasma nitric oxide level "direct relationship". The plasma nitric oxide level is directly related while s carotene, vitamin C and a-tocopherol is inversely related with duration of substances abuses. |
