The Amino and Deamino Analogues of 8-D-Homoarginine-Vasopressin with p-Substituted Phenylalanine in Position 2 in Activation of Factor VIII and Tissue Plasminogen Activator in Primates

Autor:	Jiří Velek, Tomislav Barth, Hans Vilhardt, Miroslava Žertová, Zdenko Procházka
Rok vydání:	1995
Předmět:	medicine.medical_specialty Vasopressin Endocrinology Biochemistry Chemistry Internal medicine medicine Phenylalanine General Chemistry Tissue plasminogen activator medicine.drug
Zdroj:	Collection of Czechoslovak Chemical Communications. 60:697-704
ISSN:	1212-6950 0010-0765
DOI:	10.1135/cccc19950697
Popis:	The replacement of L-Tyr in dDAVP by L-Tyr(Me), L- or D-Phe(pMe), L- or D-Phe(pEt) in combination with substitution of D-arginine by D-homoarginine resulted in dissociation of Factor VIII and tPA activating properties or in abilities to decrease the levels of circulating Factor VIII and tPA levels in blood of squirrel monkeys.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3e719eb765da992d2b8de11c0a74fcd1 https://doi.org/10.1135/cccc19950697 Zobrazit plný text záznamu