Gene Expression Analysis in Inflamed and Non-inflamed Hemodialysis (HD) Patients Using a cDNA Microarray

Autor:	Peter Stenvinkel, Astrid Seeberger, Louise Nordfors, Olof Heimbürger, Roberto Pecoits-Filho, Bengt Lindholm, D Hauzenberger
Rok vydání:	2003
Předmět:	business.industry medicine.medical_treatment Proteolytic enzymes Hematology Molecular biology Cytokine Nephrology Complementary DNA Gene expression Gene chip analysis Medicine business Receptor Cytokine receptor Gene
Zdroj:	Hemodialysis International. 7:73-104
ISSN:	1492-7535
DOI:	10.1046/j.1492-7535.2003.01269.x
Popis:	Systemic inflammation is an independent predictor of mortality in HD patients, and a better understanding of its pathogenetic pathways and identification of targets for intervention are needed. The cDNA microarray technology has recently been used to profile gene expression, and examines simultaneously a broad variety of genes that could determine biological and pathogenetic processes. To investigate the gene expression profile in white blood cells of eight persistently inflamed (CRP > 10 mg/L for 12 months) HD patients compared to eight non-inflamed patients (CRP
Databáze:	OpenAIRE
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