Real-world adjuvant chemotherapy patterns and outcomes among elderly patients with resected early non-small-cell lung cancer in the USA

Autor:	Jay M Lee, Rongrong Wang, Ann Johnson, Sarika Ogale, Matthew Kent, Janet S Lee
Rok vydání:	2023
Předmět:	Cancer Research Oncology General Medicine
Zdroj:	Future Oncology. 19:37-47
ISSN:	1744-8301 1479-6694
DOI:	10.2217/fon-2022-0845
Popis:	Background: This study investigated real-world treatment patterns and overall survival (OS) in early non-small-cell lung cancer patients and the association between OS and time-to-adjuvant-treatment. Materials & methods: This retrospective study using Surveillance, Epidemiology and End Results data linked with Medicare claims included resected early non-small-cell lung cancer patients between 2010 and 2015. Unadjusted OS analyses used Kaplan–Meier curves; adjusted OS analyses used extended Cox proportional hazards models. Results: Only 54–71% of stage II–IIIA patients received any adjuvant treatment. Adjusted risk of death was higher when starting treatment outside 6–8 weeks after surgery (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3bf444b11c283644dbc447105119eafb https://doi.org/10.2217/fon-2022-0845 Zobrazit plný text záznamu