Elektronenoptische Untersuchungen zur Kollagenfaserstruktur des menschlichen Trommelfells beim Adhäsivprozeß

Autor:	Pau Hw, Schaeg G, Mensing K, Hartwein J
Rok vydání:	1990
Předmět:	Lamina propria Chemistry Cholesteatoma Anatomy medicine.disease law.invention medicine.anatomical_structure Otitis Otorhinolaryngology law medicine Collagenase Adhesive Fiber Electron microscope medicine.symptom Process (anatomy) medicine.drug
Zdroj:	Laryngo-Rhino-Otologie. 69:333-336
ISSN:	1438-8685 0935-8943
DOI:	10.1055/s-2007-998203
Popis:	In an EM study, the collagen fiber arrangement of the lamina propria in adhesive otitis media was investigated. Nine biopsies of the tympanic membrane were taken intraoperatively, and compared with two normal ones. The physiological specimens showed a regular arrangement of collagen fibrils and fibers, the typical network of the lamina propria. This confirmed results reported previously. In all adhesive otitis media samples the regular structure of the fiber arrangement was disturbed. Degenerative processes were to be found in the form of hyaline changes, with the network character of the fibers no longer in evidence. In one specimen a mass of microfibrils was observed, which was possibly a sign of reparative processes. The pathohistological findings in adhesive otitis media may be due to mechanical stresses (tubal function). Aside from that, they may also be caused by the biochemical influence of specific collagenases, which have been found by several authors in secretory otitis was well as in cholesteatoma.
Databáze:	OpenAIRE
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