Investigation of a novel diamine based chiral auxiliary in the asymmetric alkylation of ketones

Autor:	Christina M. McSweeney, Gerard P. McGlacken, Sarah L. Clarke
Rok vydání:	2014
Předmět:	Chiral auxiliary Organic Chemistry High selectivity Alkylation Ring (chemistry) Catalysis Pyrrolidine Inorganic Chemistry chemistry.chemical_compound chemistry Aldol reaction Diamine Organic chemistry Physical and Theoretical Chemistry
Zdroj:	Tetrahedron: Asymmetry. 25:356-361
ISSN:	0957-4166
DOI:	10.1016/j.tetasy.2014.01.006
Popis:	A novel chiral auxiliary containing a pyrrolidine ring has been utilised in the preparation of various chiral ketones with good to excellent enantioselectivities (up to 92%). It has been successfully employed in aldol and Michael reactions giving moderate to high selectivity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3b49238d5234fc83af4543eb946445e0 https://doi.org/10.1016/j.tetasy.2014.01.006 Zobrazit plný text záznamu Full Text from ScienceDirect