Ultrastructural and functional changes in rat brain synaptosomes during electrical stimulation in vitro

Autor:	Rodina Vi, L. K. Salata, O. M. Pozdnyakov, Rozhanets Vv, Glebov Rn
Rok vydání:	1980
Předmět:	medicine.medical_specialty Phosphodiesterase Endogeny Stimulation General Medicine Biology Rat brain General Biochemistry Genetics and Molecular Biology In vitro Cyclic nucleotide phosphodiesterase activity Endocrinology Internal medicine medicine Ultrastructure Liberation
Zdroj:	Bulletin of Experimental Biology and Medicine. 89:108-111
ISSN:	1573-8221 0007-4888
Popis:	Electrical stimulation of a suspension of rat brain synaptosomes leads to significant Ca++-dependent liberation of endogenous noradrenalin and to a Ca++-dependent increase in its concentration in the synaptosomes themselves. Cyclic nucleotide phosphodiesterase activity is lowered significantly under these same conditions. No disturbance of synaptosomal ultrastructure is found during stimulation. An increase in the number of electron-dense synaptosomes is observed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3b12ef40303e30b8402fc5aea48287ca https://doi.org/10.1007/bf00830991 Zobrazit plný text záznamu Full text from SpringerLink