The value of pretreatment glucose-to-lymphocyte ratio for predicting survival of metastatic gastric cancer

Autor:	Zekeriya Hannarici, Ali Yılmaz, Mehmet Emin Buyukbayram, Aykut Turhan, Alperen Akansel Çağlar, Mehmet Bilici, Salim Başol Tekin
Rok vydání:	2023
Předmět:	Cancer Research Oncology General Medicine
Zdroj:	Future Oncology. 19:315-325
ISSN:	1744-8301 1479-6694
DOI:	10.2217/fon-2022-0579
Popis:	Aim: To demonstrate the prognostic importance of glucose-to-lymphocyte ratio (GLR) in metastatic gastric cancer (mGC). Methods: Retrospectively, 159 mGC patients were enrolled. Kaplan–Meier curve and Cox regression analysis were used to determine the prognostic value of the systemic immune inflammation index (SII), neutrophil-to-lymphocyte ratio (NLR), prognostic nutritional index (PNI) and GLR. Results: Progression-free survival (PFS) and overall survival (OS) were associated with NLR, PNI, SII and GLR by univariate analysis. Moreover, OS was associated with Eastern Cooperative Oncology Group performance status and the chemotherapy regimen. In multivariate analysis, only GLR was found to be independently prognostic for both PFS and OS. Conclusion: In mGC, GLR may be a new prognostic marker for both OS and PFS.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3ad35c00624bed0781e734b40f2def39 https://doi.org/10.2217/fon-2022-0579 Zobrazit plný text záznamu