Progress in recent development of stereoselective synthesis of β2-amino acid derivatives from β-nitroacrylate derivatives

Autor: Hao Wei Zeng, Ping Yu Wu, Hsyueh Liang Wu
Rok vydání: 2020
Předmět:
Zdroj: Organic & Biomolecular Chemistry. 18:2991-3006
ISSN: 1477-0539
1477-0520
Popis: The synthesis and properties of β-amino acids have drawn considerable attention owing to their ubiquitous presence in naturally occurring products of biological importance. While β3-amino acids can be readily prepared from α-amino acids via one-carbon homologation, the synthesis of β2-amino acids generally requires multistep efforts. This review focuses on the recent advances in the synthesis of β2-amino acids and their derivatives from substituted β-nitropropionate analogues obtained from the stereoselective transformation of β-nitroacrylates.
Databáze: OpenAIRE