Present-day professional lead polyneuropathy — chronic demyelinating disease of peripheral nervous system

Autor:	J. I. Borzunova, R. G. Obraztsova
Rok vydání:	1997
Předmět:	Pathology medicine.medical_specialty medicine.anatomical_structure business.industry Lead Polyneuropathy Peripheral nervous system Demyelinating disease medicine General Medicine medicine.disease business
Zdroj:	Neurology Bulletin. :64-67
ISSN:	2304-3067 1027-4898
DOI:	10.17816/nb79897
Popis:	Relatively high positive correlation between lead content in biologic environment and indices of porphyrinic exchange in patients with neurogenic form of chronic polyneuropathy has been determined. In risk group such correlation was absent. Clinical symptoms, change in electric neuromyography, indices of porphyrinic exchange and lead content in biologic environment has been studied in 92 workers engaged in making lead and exposed to small average concentrations of it close to the limiting permissible concentration during the working day. Progression of chronic lead intoxication, the initial form of which clinically reveals in 124 years by vegetosensoric polyneuropathy of upper and lower extremities and intrinsic changes in electric neuromyography indices has been determined. Isolated symptoms of polyneuropathy and lowering of the indicated parameters of electric neuromyography by 510% are revealed in preclinical stage (risk signs). The nature of electric neuromyography changes points to segmental myelinopathy.
Databáze:	OpenAIRE
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