Prevalence and correlation of conventional and lupus-specific risk factors for cardiovascular disease in Chinese systemic lupus erythematosus patients
Autor: | Tu Yt, Yali Ren, Guangfen Xu, X. Tang, Juan Tao, Laurence T. Yang, Y. Wang, X. He |
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Rok vydání: | 2011 |
Předmět: |
Creatinine
medicine.medical_specialty Systemic lupus erythematosus Lupus erythematosus Proteinuria business.industry Case-control study Hydroxychloroquine Dermatology medicine.disease chemistry.chemical_compound Infectious Diseases Elevated serum creatinine chemistry immune system diseases Internal medicine Diabetes mellitus Immunology medicine medicine.symptom skin and connective tissue diseases business medicine.drug |
Zdroj: | Journal of the European Academy of Dermatology and Venereology. 26:95-101 |
ISSN: | 0926-9959 |
Popis: | Background It has become clear that the morbidity and mortality of patients with lupus and cardiovascular disease (CVD) have substantially increased. Therefore, we designed a retrospective case–control study to assess the prevalence of traditional and lupus-specific risk factors for CVD in Chinese systemic lupus erythematosus (SLE) patients. Objective To identify the prevalence and correlation of conventional and lupus-specific risk factors for CVD in Chinese SLE patients. Methods One hundred and thirty-nine patients with SLE were enrolled in the study. They were compared with 139 age and gender-matched controls, who had no history of SLE or CVD. Among 139 SLE patients, there were 38 with CVD. We compared them with 38 SLE patients without CVD, matching for disease duration and age. Data regarding classic and lupus-specific risk factors were assessed between the two groups. Results Hypertension, serum creatinine and diabetes mellitus were more prevalent among SLE than the controls (P |
Databáze: | OpenAIRE |
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