| Autor: |
Van Thuan Hoang, Sékéné Badiaga, Thi Loi Dao, Didier Raoult, Ndiaw Goumbala, Philippe Brouqui, Tran Duc Anh Ly, Philippe Gautret, Hervé Tissot-Dupont, Linda Hadjadj, Jean-Marc Rolain |
| Rok vydání: |
2020 |
| Předmět: |
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| DOI: |
10.1101/2020.09.22.20199729 |
| Popis: |
We aimed to assess the prevalence of pathogenic bacteria and resistance genes in rectal samples collected among homeless persons in Marseille, France. In February 2014 we enrolled 114 sheltered homeless adults who completed questionnaires and had rectal samples collected. Eight types of enteric bacteria and 15 antibiotic resistance genes (ARGs) were sought by real-time polymerase chain reaction (qPCR) performed directly on rectal samples. ARG-positive samples were further tested by conventional PCR and sequencing. We evidenced a 17.5% prevalence of gastrointestinal symptoms, a 9.6% DNA-prevalence of enteric bacteria carriage, includingEscherichia colipathotypes (8.7%) andTropheryma whipplei(0.9%). Only 2 persons carriedblaCTX-M-15resistance genes (1.8%), while other genes, including carbapenemase-encoding genes and colistin-resistance genes, (mcr-1 tomcr-6, mcr-8) were not detected. Our results suggest that sheltered homeless persons in Marseille do not have a high risk of harbouring gastrointestinal antibiotic resistant bacteria. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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