| Autor: |
Silvère Ngouela, Bruno Ndjakou Lenta, Etienne Tsamo, Yanick F. Fongang, Angelbert F. Awantu, Norbert Sewald, Jean Duplex Wansi, Tobias Bogner |
| Rok vydání: |
2011 |
| Předmět: |
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| Zdroj: |
ChemInform. 42 |
| ISSN: |
0931-7597 |
| DOI: |
10.1002/chin.201142188 |
| Popis: |
Phytochemical investigation of the stem bark and fruits of Dialium excelsum led to the isolation of a new triterpenoid, named dialiumoside (1), together with twelve known compounds (2-13). The structure of the new compound as well as those of the known compounds were established by means of spectroscopic methods and by comparison with previously reported data. Compounds 1-13 were tested for their cytotoxic activity against the human cervix carcinoma KB-3-1 cells and the related multi drug-resistant P-gp-expressing KB-V1 cells. Compounds 1 and 13 showed weak biological activity in cytotoxicity assays while other compounds were inactive. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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