Selective sentinel lymph node biopsy in male breast cancer

Autor: J. M. Sousa Vaquero, Juan José Martín-Marcuartu, Rosa María Álvarez-Pérez, J.M. Jiménez-Hoyuela García
Rok vydání: 2018
Předmět:
Zdroj: Revista Española de Medicina Nuclear e Imagen Molecular (English Edition). 37:146-150
ISSN: 2253-8089
DOI: 10.1016/j.remnie.2017.11.019
Popis: Objective To evaluate the reproducibility of the sentinel lymph node (SLN) technique in male breast cancer. Material and methods We retrospectively analyzed 21 male patients diagnosed with breast cancer in our hospital from 2008 to 2016 with, at least, 18 months follow-up. Fifteen patients underwent selective sentinel lymph node biopsy (SLNB) following the usual protocols with peritumoral injection of 18.5–111 MBq of 99mTc-nanocoloides and acquisition of planar images 2 h after the injection. In 2 cases it was necessary to perform a SPECT/CT to locate the SLN. Immunohistochemistry and molecular techniques (OSNA) were used for their analysis. Six patients did not undergo SLNB because they had pathological nodes or distant disease at the time of diagnosis. Results SLNB was performed in 15 patients. The SLN was negative in 6 patients and positive in the remaining 9. Three patients with positive SLNB did not need axillary lymphadenectomy because of the low number of copies by molecular analysis OSNA. Axillary lymphadenectomy was performed in the remaining 6 patients with the result of 4 positive axillary lymphadenectomies and 2 that did not show further extension of the disease. Conclusions According to our experience, SLNB in males is a reproducible, useful, safe and reliable technique which avoids unnecessary axillary lymphadenectomy and prevents the appearance of undesirable effects.
Databáze: OpenAIRE
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