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Purpose: To compare the early therapeutic effect of intravitreal ranibizumab (IVR) injection in eyes with diabetic macular edema (DME) of different patterns determined by spectral-domain optical coherence tomography (SD-OCT). Materials and Methods: Medical records of nonproliferatif diabetic retinopathy (NPDR) patients who had a single IVR injection for DME were analyzed retrospectively. Eyes with a clinically significant DME and a central foveal thickness (CFT) ≥ 250 µm determined by SD-OCT were included. Best-corrected visual acuity (BCVA), CFT and total macular volume (TMV) values before and after the injection were recorded. Eyes were divided into sponge-like diffuse retinal thickening (DRT), cystoid macular edema (CME) and serous retinal detachment (SRD) groups according to SD-OCT. Sub-analyzes were performed to exclude the effect of baseline CFT disparity. Results: A total of 101 eyes (44 DRT, 40 CME and 17 SRD) were included in the study. While there was no difference between the baseline BCVA and TMV values (p>0.05), the CFT values were ranked as SRD, CME and DRK (p |
