Hypertension and Increased Left Ventricular End-diastolic Pressure Influence Arterial Stiffness

Autor: Tae Hoon Ahn, Wook-Jin Chung, Bong Roung Kim, In Suk Choi, Mi-Seung Shin, Yae Min Park, Kyoung Hoon Lee, Seung Hwan Han, Woong Chol Kang
Rok vydání: 2013
Předmět:
Zdroj: Journal of Lipid and Atherosclerosis. 2:9
ISSN: 2288-2561
2287-2892
DOI: 10.12997/jla.2013.2.1.9
Popis: Objective: There have been few studies regarding the relationship between arterial stiffness and left ventricular end-diastolic pressure (LVEDP). In the current study, we evaluated the relationship between the LVEDP and arterial stiffness in patients with hypertension (HTN). Methods: Group I (n=34) included patients with a normal E/E’ (≤8) without HTN, group II (n=31) included patients with an elevated E/E’ (>8) without HTN, group III (n=20) included patients with a normal E/E’ (≤8) with HTN, and group IV (n=49) included patients with an elevated E/E’ (>8) with HTN. Aortic distensibility (AD) and the right brachial-ankle pulse wave velocity (baPWV) were measured. Results: The mean age was 46.0±11.3 years. The mean value of AD was significantly lower in the group III compared to the group I. The group IV showed significantly lower AD compared to the group II. The group III demonstrated higher baPWV compared to the group I (1422±182 cm/sec vs. 1186±178 cm/sec, p
Databáze: OpenAIRE