| Popis: |
Background: Persons living with HIV (PLWHIV) on highly active antiretroviral treatments (HAART) may require specialized care based on health and demographic indicators. This study investigated the association of co-morbidities, race, weight status, gastrointestinal (GI), and cardiovascular symptoms (CV) and among PLWHIV. Methods: The Symptom Checklist, Co-Morbidity, and Sociodemographic Questionnaires were used to assessed weight status, GI, and CV symptoms among 283 PLWHIV. Data were analyzed using Latent Class Analysis on John's Macintosh Project 13 Platform. Results: Participants were majority Black (50%), 69% male, and 35% AIDS diagnosed. Ages were 25 to 66. Clusters included least symptomatic status, weight gain, and weight loss by Black and non-Black participants. The non-Black weight gain cluster reported a higher incidence of AIDS (70.6% vs 38.2%), nausea (70.6% vs 17.6%), diarrhea (70.6% vs 26.5%), and shortness of breath (58.8% vs 20.6%) compared to the Black weight gain cluster. The Black weight loss cluster reported a higher incidence of CV symptoms such as chest palpitations (42.2% vs 2.7%), chest pain (44.4% vs 8.1%), and shortness of breath (73.3% vs 35.1%), and a higher incidence of all GI symptoms with the most prominent being diarrhea (71.1% vs 48.6%) compared to the non-Black weight loss cluster. Conclusions: The existing racial disparities in health-related quality of life for PLWHIV may be improved through precision health and nutrition modifications. Continued research is needed investigating differential health outcomes among PLWHIV on HAART.Clinical Trial Registration Number: NCT00222716 |
