| Autor: | Margarita Topalovski, Philip T. Krmpotich, Rachel Cherian, Allan P. Weston, Anita Dixon |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
medicine.medical_specialty
Physiology Esophageal disease business.industry Incidence (epidemiology) Gastroenterology Intestinal metaplasia Hepatology medicine.disease digestive system digestive system diseases surgical procedures operative medicine.anatomical_structure Dysplasia Barrett's esophagus Metaplasia Internal medicine otorhinolaryngologic diseases medicine medicine.symptom Esophagus business neoplasms |
| Zdroj: | Digestive Diseases and Sciences. 42:597-602 |
| ISSN: | 0163-2116 |
| DOI: | 10.1023/a:1018811512939 |
| Popis: | The prevalence of cardia versus noncardiagastric intestinal metaplasia in patients with Barrett'sesophagus was assessed prospectively. Four-quadrantbiopsies were obtained from the cardia from 119consecutive patients with Barrett's esophagus and 64control patients. Gastric surveillance biopsies wereobtained in 108 of the Barrett's patients and 58 controlpatients. There was a significantly greater prevalence of cardia intestinal metaplasia inshort-segment Barrett's (10.2%), but not traditionalBarrett's (3.3%), compared to control patients (0%) (P= 0.009). Dysplastic changes were significantly morefrequent in the metaplastic epithelium within theesophagus than in the cardia (P < 0.0001). Asignificantly greater prevalence of noncardia intestinalmetaplasia compared to cardia intestinal metaplasia wasfound in each of the three groups of patients;however, the prevalence of noncardia intestinalmetaplasia between short-segment, traditional, andcontrol patients was not significantly different. Cardiaintestinal metaplasia was an infrequent finding inpatients with Barrett's esophagus and appears to developindependently from that in the remainder of thestomach. |
| Databáze: | OpenAIRE |
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