Loss of ETV1/ER81 in motor neurons leads to reduced monosynaptic inputs from proprioceptive sensory neurons

Autor:	David R. Ladle, Simon Hippenmeyer
Rok vydání:	2023
Předmět:	Physiology General Neuroscience
Zdroj:	Journal of Neurophysiology. 129:501-512
ISSN:	1522-1598 0022-3077
DOI:	10.1152/jn.00172.2022
Popis:	In the stretch reflex circuit, proprioceptive afferents establish monosynaptic connections with spinal motor neurons that project to the same muscle. The ETS transcription factor ETV1/ER81 is expressed in all proprioceptive afferents, but only certain groups of motor neurons in the spinal cord of the mouse. Conditional ablation of Er81 expression from motor neurons reveals selective defects in the establishment of stretch reflex connections within motor pools that would normally express Er81.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::358ae9f93d9bbd38f79848d3b943029b https://doi.org/10.1152/jn.00172.2022 Zobrazit plný text záznamu