| Autor: |
Mai Mustafa, Amin Amin, Mahmoud Seyam, Emmy Abdelfatah, Yara Mahjoub, Ramy Gayed, Shenoda Yacoub, Ahmed Sabry, Rawan Elsayed, Reem J. Husseiny, Rahma Hassan Galal, Fady Mishriky, Marihan Ghazy, Maram Rajab, Verina Fouad, Rokaya El-Sayed, Doaa Massoud, Peter Kelada, Taquwa Aly, Yousef Husseiny, Mariem Arsanyous, Alaa Saud, Joseph Shehata, Basant Eltaher, Febronia Nasry, Mariam Messiha, Omnia Mohamed, Mark Michael, Antoine Fakhry AbdelMassih, Aya Kamel, Shahd Ragab, Rafeef Hozaien, Esraa Menshawey, Marian Eesa, Nada AlShehry, Nadine Elgamal, Nourhan Hassan, Mostafa AmanAllah, Sherry Rateb, Omnya Mahmoud Aly, Hesham Sheashaa, Noha Abdelmoneim, Assem Kassim, Merna Luis, Mayada Elfishawy, Amr Elkhateb, Lauren Nathan, Elaria Yacoub, Rania Abdelaziz, Mariam Abdelaziz, Alaa Amr, Nada Ali, Youssef Nada, Aia Mohamed Hanoura, Passant Elshawarbi, Areeg ElShaarawy, Estfana Eskandar, Rahma Menshawey, Sara Tayssir, Ahmed El-Maghraby, Hutaf Jaber, Reem Yasser, Rana AbdelHaleem, Nadine El-Husseiny, Kirollos Badr, Omar Medhat, Nada Hassan, Noha M. Khalil |
| Rok vydání: |
2020 |
| Předmět: |
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| DOI: |
10.21203/rs.3.rs-108776/v1 |
| Popis: |
Background: As more than 37 million confirmed cases and 1 million deaths worldwide from COVID-19, we flied to think about supporting immunity, So, there are more than 150 coronavirus vaccines and clinical trials are being developed. The success of those vaccines depends mainly on immunologic memory. People who are at high risk of re-infection with COVID-19 don’t show any evidence of having B-cell memory. 10-20% of infected patients don’t develop antibody response. randomized controlled trials and cross-sectional studies proved variant results about the effect of chronic exercise on vaccination function.The aim of this review is to suggest that exercise is an important adjuvant strategy for prevention of re-infection and for development of better protective responses following vaccination.Methods: Embase, Medline and the Cochrane Central Register were used to search for specific keywords such as “COVID-19” OR “SARS-CoV-2” AND “Re-infection” for relevant publications up to 1st of Nov. 2020. The systematic review was performed using PRISMA protocol.Results: According to inclusion criteria, 6 case reports from search and one case from a press conference were identified. The average age of re-infected patients was 36 years. The average intervening period between initial infection and reinfection was 105 days. 75% of cases who have been tested for antibodies after 1st infection were negative, and turned seropositive after second infection. 57% of cases developing re-infection had worse clinical manifestation.Conclusion: Regular moderate intensity exercise not only can enhance the secondary antibody response of B cell memory but also decrease the severity of re-infection and the adverse reactogenicity of potential vaccines under development. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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