The Effect of Subinhibitory Concentrations of Clindamycin on the Adherence and Glycocalyx of Staphylococcus Aureus and Bacteroides Species in Vitro and in Vivo

Autor: J. W. Costerton, Mayberry-Carson Kj, D. W. LambeJr., Mayberry Wr, Tober-Meyer B
Rok vydání: 1987
Předmět:
Zdroj: Antibiosis and Host Immunity ISBN: 9781461290582
DOI: 10.1007/978-1-4613-1901-6_4
Popis: The adherence of bacteria to biologically inert surfaces may result in a tenacious and irreversible binding (14). In some systems, this irreversible binding involves the production of bacterial exopolysaccharides which are known also as glycocalyx, or slime. Since the glycocalyx condenses radically during dehydration in preparation for transmission electron microscopy, it has been an elusive structure to demonstrate on bacteria. However, specific antibodies were used by Bayer and Thurow (1) and Mackie et al. (10) to prevent the dehydration collapse of the glycocalyx. This technique gave a true appreciation of the extent of the glycocalyx produced by many genera and species of bacteria.
Databáze: OpenAIRE