Influence of correction of secondary hyperparathyroidism on the pulse wave indicators and mineral density of bone tissue in middle‑aged women with uncomplicated arterial hypertension

Autor:	K. P. Lazarieva, Yu. V. Rudenko, O. I. Nishkumay, G. V. Mostbauer, P. Lazariev, K. M. Amosova
Rok vydání:	2019
Předmět:	Bone mineral medicine.medical_specialty business.industry Urology Parathyroid hormone medicine.disease vitamin D deficiency Trabecular bone score Arterial stiffness Vitamin D and neurology Medicine Secondary hyperparathyroidism business Pulse wave velocity
Zdroj:	UMJ Heart & Vessels. :13-22
ISSN:	2521-6910 1727-5717
Popis:	The aim — to assess the effect of correction of secondary hyperparathyroidism on the background of deficiency and insufficiency of 25 (OH) vitamin D on the parameters of central blood pressure (BP) and pulse wave, bone mineral density (BMD) in elderly patients with controlled uncomplicated arterial hypertension (AH).Materials and methods. The study included 44 women of middle age (69.04 ± 0.72 years) with AH of stage II, 2nd degree (main group) and 30 practically healthy patients (control group) of middle age (69.0 ± 1.21 years). The duration of the postmenopausal period in the main group averaged 18.40 ± 0.85 years, in the control group — 19.40 ± 1.18 years (p > 0.05). At the time of randomization AH was controlled, patients received antihypertensive therapy (AHT) based on a fixed combination of dihydropyridine calcium channel blocker (CCB) and thiazide diuretic (Aryfam, Servier, France) at the dose of 5 mg/1.5 mg or 10 mg/1.5 mg (BP levels
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::346ca713e1f38b751bfafe6795a4c4fb https://doi.org/10.30978/hv2019-1-13 Zobrazit plný text záznamu