A study of the relation between the limit of detection and the limit of quantitation in inductively coupled plasma spectrochemistry

Autor:	M. Carré, S. Excoffier, Jean-Michel Mermet
Rok vydání:	1997
Předmět:	Detection limit Chromatography Chemistry Calibration curve Analytical chemistry Linearity Repeatability Mass spectrometry Atomic and Molecular Physics and Optics Analytical Chemistry Spectrochemistry Limit (mathematics) Inductively coupled plasma Instrumentation Spectroscopy
Zdroj:	Spectrochimica Acta Part B: Atomic Spectroscopy. 52:2043-2049
ISSN:	0584-8547
DOI:	10.1016/s0584-8547(97)00114-6
Popis:	The limit of quantitation based on a repeatability threshold concept is compared with the limit of detection in induction coupled plasma atomic emission spectrometry (ICP-AES) and induction coupled plasma mass spectrometry (ICP-MS). A 5%-based limit of quantitation would normally correspond to 10 times the 3-σ based limit of detection. However, because of a possible lack of linearity of the calibration graph at low concentrations, some additional noise not taken into consideration and the possible use of time-correlated multichannel detection, this ratio of 10 cannot be used in every case. It is suggested that a suitable way of determining the limit of quantitation is to establish the plot of the percentage relative standard deviation (RSD) of the net signal as a function of the concentration in a range from the limit of detection to 50 times this limit.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3416a2354da5a5700c9bf8a4a9d8f1c1 https://doi.org/10.1016/s0584-8547(97)00114-6 Zobrazit plný text záznamu Full Text from ScienceDirect