A case of multiple cranial nerve palsies
| Autor: | Anupam Kanodia, Bhargavi Ramanujam, Kavneet Kaur, Deepti Vibha, Manish Modi, Manjari Tripathi, Madhavi Tripathi, Snigdha Komakula, Ajay Garg, Saranya B. Gomathy, Hitesh Verma, M. C. Sharma, Arunmozhimaran Elavarasi, Rajesh Kumar Singh |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test business.industry Meninges Lymphocytic pleocytosis General Medicine medicine.disease 03 medical and health sciences Skull Osteosclerosis 0302 clinical medicine medicine.anatomical_structure Cerebrospinal fluid Positron emission tomography Biopsy Hypermetabolism medicine 030212 general & internal medicine Neurology (clinical) Radiology business 030217 neurology & neurosurgery |
| Zdroj: | Practical Neurology. 21:523-531 |
| ISSN: | 1474-7766 1474-7758 |
| DOI: | 10.1136/practneurol-2021-003069 |
| Popis: | Multiple cranial nerve palsies have many possible causes, including infective, inflammatory, neoplastic and infiltrative diseases of the meninges or skull base. We present the clinicopathological conference of a 27-year-old man with a smouldering course of sequential cranial nerve palsies. His imaging showed dural thickening and osteosclerosis of the skull base with otomastoiditis. Cerebrospinal fluid showed lymphocytic pleocytosis with reduced glucose and normal protein concentrations. There was a possible response to corticosteroids and anti-tubercular treatment. Initial biopsy from the thickened and enhancing dura was unremarkable. His condition deteriorated after the steroids were tapered; MR imaging showed progression of lesions and positron emission tomography showed intense hypermetabolism. Subsequently, a diagnostic test revealed the final diagnosis. This case was presented at the All India Institute of Medical Sciences’ monthly clinicopathological conference series in February 2021. |
| Databáze: | OpenAIRE |
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