EFFECTS OF PARTIAL LIQUID VENTILATION AND INHALED NITRIC OXIDE IN PIGLETS WITH MECONIUM ASPIRATION. † 1453

Autor:	Avash J. Singh, Keith J. Barrington, Neil N. Finer, Philip C. Etches
Rok vydání:	1996
Předmět:	Cardiac output business.industry Oxygenation Nitric oxide chemistry.chemical_compound Perfluorodecalin chemistry Meconium Anesthesia Pediatrics Perinatology and Child Health Breathing Medicine Partial liquid ventilation Positive pressure ventilation business
Zdroj:	Pediatric Research. 39:245-245
ISSN:	1530-0447 0031-3998
DOI:	10.1203/00006450-199604001-01476
Popis:	Partial liquid ventilation (PLV) may shortly be used for infants with meconium aspiration (MAS). We studied the effects of PLV and inhaled nitric oxide (iNO) over 4 h in a newborn piglet MAS model. 24 piglets were anesthetized, and instrumented for monitoring pulmonary arterial pressure(PAP) cardiac output by thermodilution, pulmonary functions. The agent used was Perfluorodecalin[C10F18] (MultifluorR; Air Products and Chemicals Inc). Post instillation of meconium acidotic and hypoxic piglets (1-4 d age, 1-2 kg wt) were randomly assigned to 4 groups: Control Conventional positive pressure ventilation with 100% O2; iNO Conventional ventilation with 100% O2 + 40ppm NO; PLV FRC filled with perfluorodecalin, ventilated with 100%02; PLV+INO PLV + 40ppm NO. Results: Mean (SD) after meconium [Pre] and at 4 h [Post].*=p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::326478d577d11a5ee13ca57a2f1e4af3 https://doi.org/10.1203/00006450-199604001-01476 Zobrazit plný text záznamu