Free thyroid transfer: Short-term results of a novel procedure to prevent post-radiation hypothyroidism
| Autor: | Hadi Seikaly, Rufus Scrimger, Hani Al-Marzouki, Brittany Barber, Mark L. Urken, Jeffrey R. Harris, Daniel A. O’Connell, Jacques Romney |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
business.industry medicine.medical_treatment Head and neck cancer Thyroid Thyroidectomy chemistry.chemical_element Technetium medicine.disease Ablation 030218 nuclear medicine & medical imaging Surgery 03 medical and health sciences Dissection 0302 clinical medicine Endocrinology medicine.anatomical_structure Otorhinolaryngology chemistry Forearm 030220 oncology & carcinogenesis Internal medicine medicine business Prospective cohort study |
| Zdroj: | Head & Neck. 39:1234-1238 |
| ISSN: | 1043-3074 |
| Popis: | Background The incidence of radiation-induced hypothyroidism (RIH) in patients with head and neck cancer is >50%. The purpose of this study was to assess the long-term efficacy of free thyroid transfer (FTT) for prevention of RIH in patients with head and neck cancer. Methods Hemithyroid dissection was completed in 10 patients with advanced head and neck cancer undergoing ablation, radial forearm free flap (RFFF) reconstruction, and postoperative radiotherapy (RT). The hemithyroid was anastomosed to the donor site vessels in the forearm. Thyroid laboratory testing and technetium (Tc) scans were performed 6 weeks and 12 months postoperatively to establish functional integrity. Results FTT was successfully performed in 9 of 10 recruited patients. Postoperative Tc scans demonstrated strong Tc uptake in the forearm donor site at 6 weeks and 12 months in all patients who underwent transplantations. Conclusion FTT is feasible with maintenance of function, and may represent a novel strategy for prevention of RIH. © 2016 Elsevier Head & Neck Published by Wiley Periodicals, Inc. Head Neck 39: 1234–1238, 2017 |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text