Production of Congenital Malformations Using Tissue Antibodies. I. Kidney Antisera

Autor:	Robert L. Brent, Vincent A. Drapiewski, Elaine Averich
Rok vydání:	1961
Předmět:	Antiserum Kidney medicine.medical_specialty Fetus Fetal Resorption Congenital malformations Biology General Biochemistry Genetics and Molecular Biology medicine.anatomical_structure Endocrinology Internal medicine medicine Gestation Antibodies i
Zdroj:	Experimental Biology and Medicine. 106:523-526
ISSN:	1535-3699 1535-3702
DOI:	10.3181/00379727-106-26390
Popis:	SummaryRabbit anti-rat kidney sera, in a prescribed dosage, injected intravenously into pregnant rats on the 8th day of gestation. resulted in severe congenital malformations in 100% of the fetuses. Larger doses caused complete fetal resorption. These antisera may produce teratogenesis by interfering with placental function.
Databáze:	OpenAIRE
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