| Popis: |
Aims and methods This study aimed to compare and correlate pharmacotherapy biomarkers’ plasma and salivary levels (appraised using colorimetric assays of Lipocalin, Nesfatin, Omentin, Oxytocin, RBP-4 (retinol-binding protein-4), Resistin, SIRT 1 (sirtuin 1), Visfatin and ZBED3 (zinc finger, BED-type (ZBED) protein 3), adiposity, and atherogenicity indices in 61 normoglycemic and newly diagnosed drug naive pre-diabetic (PreDM) MetS (metabolic syndrome) patients vs. 29 lean, and normoglycemic controls. Intergroup Comparisons was conducted by ANOVA. Spearman rank correlation was also examined. Results About three quarters of the participants were females, with gender distribution similar between the two study groups (P = 0.585). Among MetS patients, almost half were normoglycemic, about 43% were prediabetic and about 8% were diabetic. The average age of study participants was 48.6 years, with MetS group being significantly older than the control group (P |
