A hospital based cross-sectional study to assess various types of non-glaucomatous optic neuropathies

Autor: Lekh Jung Thapa, Delia DeBuc, Araniko Pandey, Anadi Khatri, Shakti Shrestha, Arjun Malla Bhari
Rok vydání: 2018
Předmět:
Zdroj: New Frontiers in Ophthalmology. 4
ISSN: 2397-2092
DOI: 10.15761/nfo.1000222
Popis: Background: There is paucity of data on non-glaucomatous optic neuropathy (NGON) from low- and middle-income countries (LMIC). This study was conducted with a purpose to collect a variety of NGON in the adult population. Methods: This was a hospital-based cross-sectional study conducted between June 2016 - December 2016. All adult patients diagnosed with NGON were included. A detailed history taking was done followed by, best corrected visual acuity testing, pupillary examination, color vision, contrast sensitivity, slit-lamp bio-microscopy and fundus evaluation under mydriasis. Visual field examination and brain/orbit imaging were performed according to the necessity of the cases. Data were analyzed using IBM-SPSS version 20. Results: There were 130 patients with NGON, but only 117 cases that had adequate data to make a diagnosis were included in our study. The total number of eyes with NGON in our study was 166. The commonest diagnosis was non-arteritic ischemic optic neuropathy (45/117). Other common causes were traumatic optic neuropathy (16/117) and optic neuritis (11/117) subsequently. Alcohol-induced optic neuropathy (3/117) and Leber’s hereditary optic neuropathy (5/117) were also suspected. They were diagnosed on the basis of most relevant clinical findings and exclusion of other causes. Two cases of pregnancy-induced pituitary apoplexy were also diagnosed. Patients with inadequate evidence to make a diagnosis were grouped as; bilateral disc edema (2), unilateral optic atrophy (2) and papilledema (19). Conclusion: The emerging burden of NGON in LMIC could not be neglected. Further research is necessary to understand the causative factors for underdiagnosis of NGON in LMIC.
Databáze: OpenAIRE