| Autor: |
Gyeong-Moon Kim, Suk Jae Kim, Oh Young Bang, Keon Ha Kim, Jeong Pyo Son, Mi Ji Lee, Chin-Sang Chung, Pyoung Jeon, Sookyung Ryoo, Kwang Ho Lee, Jihoon Cha |
| Rok vydání: |
2014 |
| Předmět: |
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| Zdroj: |
Annals of Neurology. 76:356-369 |
| ISSN: |
0364-5134 |
| Popis: |
Objective Dedicated magnetic resonance (MR) imaging (MRI) sequences for evaluation of collaterals can be generated using MR perfusion (MRP) source data. We compared a novel collateral flow imaging technique with digital subtraction angiography (DSA) for determining collateral circulation in acute stroke and evaluated the ability of MR-based collateral flow maps to predict outcomes after recanalization therapy. Methods Consecutive patients who were candidates for endovascular treatment were enrolled. A collateral flow map derived from MRP source data was generated by manual or automatic postprocessing. Collateral grading based on the collateral flow map was performed and compared with grading based on DSA. Clinical and radiological outcomes were evaluated according to MR-based collateral grading and early reperfusion (ER) status. Results There was good correlation between MRI-based and DSA-based collateral grades (weighted κ-coefficient = 0.70). Collateral status and achievement of ER were the 2 main determinants of a favorable functional outcome and neurological improvement, in addition to infarct growth. Regardless of achievement of ER, better collaterals were significantly associated with a lower modified Rankin score at day 90 (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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