MP39-15 YAP EXPRESSION PLAYS IMPORTANT ROLES IN MALIGNANT AGGRESSIVENESS BY REGULATING THE INFILTRATION OF CD57 + NATURAL KILLER CELLS, CD68 + MACROPHAGES, AND MAST CELLS AND THE EXPRESSION OF VEGF-A AND PD-L1 IN CLEAR CELL RENAL CELL CARCINOMA

Autor:	Hidenori Ito, Tomohiro Matsuo, Yasushi Mochizuki, Hiroki Kurata, Yasuyoshi Miyata, Tsubasa Kondo, Kojiro Ohba, Hideki Sakai, Junki Harada, Kensuke Mitsunari, Asato Otsubo, Yuta Mukae, Tsuyoshi Matsuda
Rok vydání:	2021
Předmět:	animal structures biology CD68 Effector business.industry Urology VEGF receptors Regulator medicine.disease Hedgehog signaling pathway Clear cell renal cell carcinoma PD-L1 medicine biology.protein Cancer research business Infiltration (medical)
Zdroj:	Journal of Urology. 206
ISSN:	1527-3792 0022-5347
DOI:	10.1097/ju.0000000000002054.15
Popis:	INTRODUCTION AND OBJECTIVE:The Hippo signalling pathway is known as a critical regulator of malignant aggressiveness, and Yes-associated protein (YAP) is the most important downstream effector in t...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2d61ad90197d9f6ac74b6e5eb1af7a4d https://doi.org/10.1097/ju.0000000000002054.15 Zobrazit plný text záznamu