| Autor: | Christophe Rousselle, Jean-Michel Scherrmann, Claude Dagenais, Salvatore Cisternino |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Pharmacology
medicine.medical_specialty biology Ratón Organic Chemistry Pharmaceutical Science Perfusion scanning Blood–brain barrier Vinblastine Surgery Multiple drug resistance medicine.anatomical_structure biology.protein medicine Molecular Medicine Pharmacology (medical) Doxorubicin Perfusion Biotechnology P-glycoprotein medicine.drug |
| Zdroj: | Pharmaceutical Research. 18:183-190 |
| ISSN: | 0724-8741 |
| DOI: | 10.1023/a:1011080418027 |
| Popis: | Purpose. This study was conducted to assess the influence of P-glycoprotein (P-gp) on brain uptake of multidrug resistance sensitive drugs using an in situbrain perfusion technique in P-gp-deficient (mdr1a[−/−]) and wild-type mice. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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