Chemism and the Role of Endocannabinoids in Physiological Processes
Autor: | Ranka Prerad, Ostoja Savić, Dušan Janičić, Aleksandar Jakovljević, Božo Krivokuća |
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Rok vydání: | 2017 |
Předmět: | |
Zdroj: | Scripta Medica. 48:77-81 |
ISSN: | 2303-7954 0350-8218 |
DOI: | 10.18575/msrs.sm.e.17.11 |
Popis: | Despite being known for 5000 years, after the records of imperial Chinese doctors, cannabinoids as a subject of scientific research experienced its rise after 1964, when delta nine tetrahydrocannabinol (Δ 9 THC) by Israeli scientists was identified. This was followed by the discovery of endogenous ligand / endocannabinoids, as well as receptors CB1 and CB2. In a broader sense, endocannabinoids act as neuromodulators and immunomodulators. They are included in the various physiological processes such as: the occurrence of pain, cognition, memory formation and neuroplasticity, physical activity, respiratory processes, appetite regulation, control and heart rate, nausea and emesis, intraocular pressure, inflammatory and immune processes (antigen recognition). |
Databáze: | OpenAIRE |
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