A phase I study of weekly irinotecan (CPT), cisplatin (CIS) and flavopiridol (F)

Autor:	David P. Kelsen, D. Colevas, Gary K. Schwartz, Manish A. Shah, Mithat Gonen, J. Winkelman, Jeremy S. Kortmansky, Sandy Yi, Robert A. Lefkowitz, Archie Tse
Rok vydání:	2004
Předmět:	Cisplatin Cancer Research biology Colorectal cancer business.industry Cancer Pharmacology medicine.disease digestive system diseases Phase i study Irinotecan Oncology Apoptosis Cyclin-dependent kinase Cancer research medicine biology.protein business medicine.drug
Zdroj:	Journal of Clinical Oncology. 22:4027-4027
ISSN:	1527-7755 0732-183X
DOI:	10.1200/jco.2004.22.90140.4027
Popis:	4027 Background: F is a cyclin dependent kinase inhibitor which potentiates CPT- and CIS-induced apoptosis, with pathologic cures in colon cancer xenografts(Motwani, et.al. Clin Cancer Res 2001). W...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2cb5a595167737e6ba38c72d596e40e5 https://doi.org/10.1200/jco.2004.22.90140.4027 Zobrazit plný text záznamu