Effects of the α-Adrenergic, Kisspeptinergic, and Melatonin Systems on the Morphofunctional State of Cells of the Adrenal Cortex in Mature Rats
| Autor: | M. G. Matvienko, N. E. Dzerzhinskii, A. S. Pustovalov, A. S. Bezlyudna |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Physiology Blocking (radio) Adrenal cortex Chemistry General Neuroscience Melatonin 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Endocrinology medicine.anatomical_structure Internal medicine Reticular connective tissue medicine α adrenergic 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Neurophysiology. 49:98-106 |
| ISSN: | 1573-9007 0090-2977 |
| DOI: | 10.1007/s11062-017-9637-7 |
| Popis: | In experiments on young mature (three-month-old) albino rats, we examined the effects of the α-adrenergic, kisspeptinergic, and melatonin systems on the morphofunctional state of the adrenal cortex. Manifestations of the effects of these regulatory factors in the three zones of the adrenal cortex were dissimilar. For the glomerular zone, the state of the α-adrenergic system and high levels of melatonin played a crucial role, while the role of the kisspeptinergic system was secondary. Kisspeptinergic regulation played a major role in the modulation of the state of cells in the fascicular zone. Simultaneously, spongyocytes of this zone were inactivated upon blocking of both the kisspeptinergic and α-adrenergic systems. Adequate levels of the activity of the α-adrenergic and kisperpinergic systems were simultaneously necessary to maintain the sufficient state of spongyocytes in the reticular zone of the adrenal cortex, while effects of melatonin were not decisively important. |
| Databáze: | OpenAIRE |
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