ChemInform Abstract: Two Novel Oleanolic Acid Saponins Having a Sialyl Lewis X Mimetic Structure from Achyranthes fauriei Root

Autor:	Yoshiteru Ida, Masumi Katsumata, Miki Nagasao, Yasuaki Hirai, Toshinori Yamamoto, Yohko Satoh, Masako Yasuda, Tetsuya Kajimoto, Naho Katada
Rok vydání:	2010
Předmět:	chemistry.chemical_classification biology Stereochemistry Active components Glycoside General Medicine Glucuronic acid biology.organism_classification Terpene chemistry.chemical_compound Sialyl-Lewis X chemistry Triterpene Achyranthes Oleanolic acid
Zdroj:	ChemInform. 30
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.199902187
Popis:	Two novel triterpene glycosides, achyranthosides E and F, were isolated as methyl esters from the root of Achyranthes fauriei, an antiinflammatory medicinal plant. Their structures were characterized as oleanolic acid glucuronides having unique substituents composed of C6H9O5 and C9H15O7, respectively, at the C-3 position of glucuronic acid. These compounds are active components which can inhibit the excess recruiting of neutrophiles to injured tissues 1,000 times more potently than sialyl Lewis X.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2af811ab3b0821b78fe39fdc2af9b80a https://doi.org/10.1002/chin.199902187 Zobrazit plný text záznamu Plný text