Right Ventricular Septal Pacing Preserves Global Left Ventricular Longitudinal Function in Comparison With Apical Pacing - Analysis of Speckle Tracking Echocardiography

Autor: Akiyoshi Ogimoto, Shinji Inaba, Makoto Saito, Takumi Sumimoto, Go Hiasa, Katsuji Inoue, Hideki Okayama, Jitsuo Higaki, Toyofumi Yoshii, Kazuhisa Nishimura, Junichi Funada, Jun Suzuki
Rok vydání: 2011
Předmět:
Zdroj: Circulation Journal. 75:1609-1615
ISSN: 1347-4820
1346-9843
Popis: Background: Right ventricular (RV) pacing alters left ventricular (LV) mechanical activation, resulting in adverse impacts on LV function. This study was aimed to investigate the acute effect of RV apical (RVA) and septal pacing (RVS) on LV dyssynchrony and function using speckle tracking echocardiography. Methods and Results: The 103 patients (749 years) with symptomatic bradyarrhythmia and preserved LV ejection fraction, and 50 age-matched control subjects were studied. All patients received a permanent pacemaker and were randomly assigned into 2 groups (RVA: n=51, RVS: n=52). After insertion, patients underwent an echocardiographic study during RV pacing. LV dyssynchrony and global strain parameters were analyzed using speckle tracking echocardiography. The QRS width and dyssynchrony indices by longitudinal and radial strain were significantly greater in RVA than in both the control and RVS. The LV longitudinal dyssynchrony index was significantly related to global longitudinal strain (GLS) among 103 patients receiving RV pacing (R2=0.25, P
Databáze: OpenAIRE