Risk factors of repetitive thoracentesis of malignant pleural effusion in naive non-small cell lung carcinoma
| Autor: | I Putu Surya Sujana, Ida Ayu Jasminarti Dwi Kusumawardani, Ni Wayan Candrawati, Ida Bagus Ngurah Rai, I Gede Ketut Sajinadiyasa, Ni Luh Putu Eka Arisanti, I Gusti Ngurah Bagus Artana |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | International journal of health sciences. :4496-4514 |
| ISSN: | 2550-696X 2550-6978 |
| Popis: | Almost 40% of Non Small Cell Lung (NSCLC) patients develop Malignant Pleural Effusion (MPE). Nowadays, clinicians prefer to perform a repetitive thoracentesis rather than a definitive procedure, which causes pleural loculations and inflammation. This study aimed to identify risk factors of repeated thoracentesis MPE in NSCLC. This was an observational analytic study with a retrospective cohort design held at Prof.Dr. I.G.N.G Ngoerah General Hospital from January 2018 to June 2022. There were 95 subjects who participated in this study. The median time of repetitive thoracentesis MPE in NSCLC is 3 days (95% CI 1,9-4). The difference in location tumor in the peripheral was 3 days (2.25-3.74) while in the central was 7 days (4.24-9.75), p=0.21. The difference in histology type, Adenocarcinoma was 3 days (1.86-4.13) while squamous cell carcinoma was 4 days (2.53-5.46), p=0.69. Pleural fluid cytology positive was 6 days (2.78-9.22) while negative was 3 days (1.83-4.16), p=0.51. The EGFR mutation positive was 4 days (2.48-5.52) while negative 3 days (1.68-4.31), p=0.78. LDH levels ≥821 IU/L was 3 days (1.49-4.50) while |
| Databáze: | OpenAIRE |
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