| Autor: |
Maja Kopczynska, Harry Unwin, Richard Pugh, Ben Sharif, Thomas Chandy, Daniel Davies, Matthew Shield, David Purchase, Samuel Tilley, Arwel Poacher, Lewis Oliva, Sam Willis, Isabelle Ray, John Hui, Bethan Payne, Eilis Wardle, Fi Andrew, Hei Priscilla Chan, Jack Barrington, Jay Hale, Joanna Hawkins, Jess Nicholas, Lara Wirt, Lowri Thomas, Megan Walker, Myat Pan, Tallulah Ray, Umair Asim, Victoria Maidman, Zeid Atiyah, Zain Nasser, Zhao Tan, Laura Tan, Tamas Szakmany, Welsh Digital Data Collection Platform Collaborators |
| Rok vydání: |
2021 |
| Předmět: |
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| DOI: |
10.21203/rs.3.rs-379786/v1 |
| Popis: |
Background: The ‘Sepsis Six’ bundle was promoted as a more deliverable tool outside of the critical care settings, but there is very little data available on the progress and change of sepsis care outside the critical care environment in the UK. Our aim was to compare the yearly prevalence, outcome and the Sepsis Six bundle compliance in patients at risk of mortality from sepsis in non-intensive care environments. Methods: Patients with a National Early Warning Score (NEWS) of 3 or above and suspected or proven infection were enrolled into four yearly 24-hour point prevalence studies, carried out in fourteen hospitals across Wales from 2016-2019. Results: Out of the 26,947 patients screened 1,651 fulfilled inclusion criteria and were recruited. The full ‘Sepsis Six’ care bundle was completed on 223 (14.0%) occasions, with no significant difference between the years. On 190 (11.5%) occasions none of the bundle elements were completed. There was no significant correlation between bundle element compliance, NEWS or year of study. One hundred and seventy (10.7%) patients were seen by critical care outreach; the ‘Sepsis Six’ bundle was completed significantly more often in this group (54/170, 32.0%) than for patients who were not reviewed by critical care outreach (168/1385, 11.6%; pConclusions: Our data suggests that despite efforts to increase sepsis awareness within the NHS, there is poor compliance with the sepsis care bundles and no change in the high mortality over the study period. Further research is needed to determine which time-sensitive ward-based interventions can reduce mortality in patients with sepsis and how can these results be embedded to routine clinical practice.Trial registration: Defining Sepsis on the Wards ISRCTN 86502304 https://doi.org/10.1186/ISRCTN86502304 prospectively registered 09/05/2016 |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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