Comparison of a treatment phase and a follow-up phase of short-contact dithranol and calcipotriol in outpatients with chronic plaque psoriasis
| Autor: | S. Anehus, R. Ashton, F. Daniel, O. B. Christensen, N.-J. Mørk |
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| Rok vydání: | 1999 |
| Předmět: |
Plaque psoriasis
Chemotherapy medicine.medical_specialty business.industry medicine.medical_treatment Dermatology medicine.disease Clinical trial chemistry.chemical_compound chemistry Psoriasis Dithranol Medicine Active treatment skin and connective tissue diseases business Adverse effect Calcipotriol medicine.drug |
| Zdroj: | Journal of Dermatological Treatment. 10:261-265 |
| ISSN: | 1471-1753 0954-6634 |
| DOI: | 10.3109/09546639909056042 |
| Popis: | Objective/Methods: The efficacy, adverse events and acceptability of microencapsulated dithranol (Micanol®), short-contact, and calcipotriol ointment, twice daily, were compared in a multicentre study in 171 outpatients with chronic, plaque-type psoriasis. An active treatment phase and a follow-up phase without active treatment were included.Results: The efficacy of calcipotriol ointment was significantly better than dithranol cream in the treatment phase. During the follow-up phase, a significantly greater proportion of patients obtaining ≤ 50% improvement from initial treatment with dithranol cream stayed in remission compared with calcipotriol ointment.Conclusion: Adverse events were limited and minor, and the acceptability of both treatments was good; dithranol cream, like calcipotriol ointment, can be used by patients at home. |
| Databáze: | OpenAIRE |
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