Prevention of SV40 Virus Tumorigenesis in Newborn Hamsters by Maternal Immunization

Autor:	V. M. Larson, Maurice R. Hilleman, W. G. Raupp
Rok vydání:	1967
Předmět:	Fetus biology viruses medicine.disease_cause Virology General Biochemistry Genetics and Molecular Biology Virus Tumor antigen Antigen Immunization In utero Immunology medicine biology.protein Antibody Carcinogenesis
Zdroj:	Experimental Biology and Medicine. 126:674-677
ISSN:	1535-3699 1535-3702
Popis:	SummaryAdministration of live SV40 virus vaccine to adult female hamsters prior to conception afforded protection of the progeny against tumorigenesis by the homologous virus given shortly following birth. The mechanism appeared to be passive transfer of maternal antibody which prevented infection. There was no apparent infection of the fetus with SV40 virus in utero and there was no detectable CF antibody in the mothers or the progeny against SV40 tumor antigen. Maternal immunization holds promise as a means for preventing tumor induction in man caused by hypothetical viral neoplastic agents.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2a78f7b27dd1cb8d8017958b6b0ad52a https://doi.org/10.3181/00379727-126-32537 Zobrazit plný text záznamu