Comparison of the efficacies of cutaneous and subcutaneous administration of tactivin for correction of secondary immunodeficiency in infants and young children

Autor: A. V. Filimonova, Bekman Em, N. A. Tyurin, V. Ya. Arion, N. A. Mazurina
Rok vydání: 1994
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 118:1193-1195
ISSN: 1573-8221
0007-4888
DOI: 10.1007/bf02444622
Popis: A method for noninvasive administration of immunomodulators, specifically, of tactivin, has been developed. The dosage form for cutaneous applications represents a special film containing the immunocorrector tactivin. Before application the film and underlying skin site are moistened with normal saline, after which the film is held with a plaster on the skin of the forearm flexor surface for 10–12 h. The optimal dose of tactivin for applications is 100μg. Comparative analysis showed that the efficacies of cutaneous and subcutaneous administration of tactivin to infants and young children are comparable according to immunological criteria and clinical results.
Databáze: OpenAIRE