Serum C-reactive Protein Predicts Early Mortality in Patients with Decompensated Cirrhosis of Liver
| Autor: | Mamun Al Mahtab, Sheikh Mohammad Noor E Alam, Atikul Islam, Narwana Khaleque, Dulal Chandra Das, M Abul Khair Yousuf |
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| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Bangladesh Medical Journal. 49:1-6 |
| ISSN: | 2219-1607 0301-035X |
| DOI: | 10.3329/bmj.v49i1.52582 |
| Popis: | Serum C-reactive protein is a marker of systemic inflammation, which has been studied to predict mortality and cirrhosis related complication in decompensated cirrhosis of liver. To evaluate the role of serum C- reactive protein as a predictor of early mortality in patients with decompensated cirrhosis of liver. This was a prospective observational study, carried out in the Department of Hepatology, Bangabandhu Sheikh Mujib Medical University, Dhaka between October 2017 to February 2019. A total of 89 patients with decompensated cirrhosis of liver were included in the study. Baseline serum CRP was measured and patients were longitudinally followed for a period of 30 days. Patients were divided into two groups, survival and non-survival. The groups were compared of CRP level, CTP score, MELD score and cirrhosis related complications. Chi-Square test was used to analyze the categorical variables and Student t-test was used to analyze continuous variables. Receiver-operator characteristic curve was used to detect serum CRP level for prediction of mortality within 30 days. The mean age was found 49.02±13.90 years in survival group and 47.52±11.30 years in non-survival group. Male patients were predominant in both groups. Total WBC count, serum CRP, serum sodium, serum bilirubin, CTP score & MELD score were statistically significant (p |
| Databáze: | OpenAIRE |
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