Ceramide: an endogenous regulator of apoptosis and growth suppresion

Autor:	Marina Y. Pushkareva, Yusuf A. Hannun, Lina M. Obeid
Rok vydání:	1995
Předmět:	Ceramide Immunology Regulator Endogeny Biology Cell biology chemistry.chemical_compound Mechanism of action chemistry Apoptosis medicine Signal transduction medicine.symptom Sphingomyelin Intracellular
Zdroj:	Immunology Today. 16:294-297
ISSN:	0167-5699
DOI:	10.1016/0167-5699(95)80184-7
Popis:	The action of several cytokines is mediated via activation of the sphingomyelin cycle of signal transduction. Ceramide, the product of this pathway, is emerging as an intracellular messenger that mediates effects on terminal differentation, apoptosis and cell-cycle arrest. Here, Marina Pushkareva, Lina Obeid and Yusuf Hannun discuss the regulation and mechanism of action of this stress-activated pathway.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::293573810798531d2b3afafdd3445633 https://doi.org/10.1016/0167-5699(95)80184-7 Zobrazit plný text záznamu Full Text from ScienceDirect