| Autor: |
Lesia Rodriguez, Lukáš Fiedler, Minxia Zou, Caterina Giannini, Aline Monzer, Zuzana Gelová, Inge Verstraeten, Jakub Hajný, Shutang Tan, Lukas Hoermayer, Lanxin Li, Maria Mar Marques-Bueno, Gergely Molnár, Tongda Xu, Ivan Kulich, Yvon Jaillais, Jiří Friml |
| Rok vydání: |
2022 |
| DOI: |
10.1101/2022.11.30.518503 |
| Popis: |
SUMMARYThe plant hormone auxin and its directional transport across tissues mediate much of the remarkably adaptive and plastic development of higher plants. Positive feedback between auxin signalling and transport is a key prerequisite for self-organizing development including flexible vascular tissue formation and directional growth responses, such as gravitropism. Here we identified a mechanistic link between cell surface ABP1-based auxin perception, the associated TMK1 kinase and PIN auxin transporters.abp1andtmk1mutants are defective in auxin-triggered phosphorylation of PIN proteins and in PIN-mediated directional auxin transport. Auxin, via ABP1, induces activation and stabilization of TMK1, thus promoting direct interaction with and phosphorylation of PIN2. Following gravistimulation, the auxin-activated TMK1 acts along the lower root side to reinforce asymmetry in PIN2-mediated auxin fluxes for gravitropic root bending. This ABP1-TMK1-dependent positive feedback on PIN-mediated directional auxin transport is fundamental for robust root gravitropism and presumably also for other self-organizing developmental processes. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
