| Autor: |
Andrés Benchetrit, Laura Walker, Roxana Depardo, Mercedes Romero, Ricardo Negroni, Alicia Arechavala, Gabriela Santiso, Emmanuel Marin, Fernando Messina |
| Rok vydání: |
2018 |
| Předmět: |
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| Zdroj: |
Revista Iberoamericana de Micología. 35:56-58 |
| ISSN: |
1130-1406 |
| DOI: |
10.1016/j.riam.2017.09.001 |
| Popis: |
A 48 year-old immunocompetent woman, who had a nodular lesion in the neck and a dense infiltrate at the lower lobe of the left lung, presented at the Mycology Unit of Muniz Hospital of Buenos Aires City. The pulmonary infiltrate disappeared spontaneously 3 months later. The histopathological study of the nodular lesion showed capsulated yeasts (mucicarmin and alcian blue positive stains) compatible with Cryptococcus. The mycological study of a new sample, obtained by a nodular puncture, allowed the isolation of yeasts, identified as Cryptococcus gattii (VGII). Latex test for Cryptococcus capsular antigen in serum was positive (1/100). CSF cultures rendered negative results. Fluconazole at a daily dose of 800mg was given during 45 days with partial improvement; as cultures from a new clinical sample were positive for Cryptococcus, the antimycotic was changed to itraconazole 400mg/day for 5 months, with an excellent clinical response. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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