| Autor: |
S Rechitsky, Joe Leigh Simpson, Anver Kuliev |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Practical Preimplantation Genetic Testing ISBN: 9783030431563 |
| Popis: |
Preimplantation HLA typing (PGT-HLA) provides patients with important option not only to avoid an inherited risk but also to establish pregnancy with an exact HLA match to benefit the affected family member. So HLA typing is now an established PGT indication, to achieve stem cell transplantation treatment of affected siblings in need for compatible transplant. It is also applied as primary indication for cases not requiring PGT-M when no HLA-compatible donor is available. The most frequent applications of PGT-HLA were for families with hemoglobinopathy and congenital immunodeficiency siblings, both resulting in total cure when compatible donor was obtained through PGT-HLA. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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