ChemInform Abstract: Palladium Enolate Umpolung: Cyclative Diacetoxylation of Alkynyl Cyclohexadienones Promoted by a Pd/SPRIX Catalyst

Autor:	Suman C. Mohanta, Hiroaki Sasai, Kazuhiro Takenaka
Rok vydání:	2014
Předmět:	Acetic acid chemistry.chemical_compound chemistry Nucleophile Ligand chemistry.chemical_element General Medicine Medicinal chemistry Oxygen atmosphere Catalysis Umpolung Palladium
Zdroj:	ChemInform. 45
ISSN:	0931-7597
DOI:	10.1002/chin.201443093
Popis:	A novel palladium-catalyzed reaction involving an unusual nucleophilic attack on a palladium enolate was developed using a spiro-bis(isoxazoline) (SPRIX) ligand. Treatment of alkynyl cyclohexadienone substrates with a Pd/SPRIX catalyst in acetic acid under an oxygen atmosphere furnished diacetoxylated benzofuranone derivatives in good yields. This cyclative diacetoxylation proceeded enantioselectively in the presence of an optically pure SPRIX ligand.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::28090664dd6216abfa3edc0e581c6bd1 https://doi.org/10.1002/chin.201443093 Zobrazit plný text záznamu Plný text