Carcinoma of the pancreas: Review of MGH experience from 1963 to 1973—Analysis of surgical failure and implications for radiation therapy
| Autor: | Joel E. Tepper, Herman D. Suit, George L. Nardi |
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| Rok vydání: | 1976 |
| Předmět: |
Cancer Research
medicine.medical_specialty medicine.diagnostic_test business.industry medicine.medical_treatment Incidence (epidemiology) Retrospective cohort study medicine.disease Surgery Radiation therapy medicine.anatomical_structure Oncology Biopsy medicine Carcinoma Adenocarcinoma Radical surgery Pancreas business |
| Zdroj: | Cancer. 37:1519-1524 |
| ISSN: | 1097-0142 0008-543X |
| Popis: | A retrospective study was done of all patients who were seen for definitive treatment of adenocarcinoma of the pancreas at the Massachusetts General Hospital from 1963 to 1973. There were a total of 145 patients. Thirty-one patients were treated with radical surgery, with a 16% operative mortality, a 5-year crude survival rate of 15%, and a local recurrence rate of 50%. Sixty-two patients were treated with biopsy alone, with no 5-year survivors. In addition, there were 35 patients who did not have a radical surgical procedure performed only because of the extent of the local disease. It is proposed that postoperative irradiation may reduce the incidence of local failure after radical surgery, and that preoperative radiation therapy or radiation therapy alone would be an appropriate treatment of those patients in whom the local extent of disease is initially too far advanced to perform radical surgery. |
| Databáze: | OpenAIRE |
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